BSC-2010 Lecture Notes - Lecture 15: Smooth Muscle Tissue, Somatic Nervous System, Tetanic Contraction

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A simple response pathway: foraging by a star-nosed mole. The interaction of muscles and skeletons in movement. Our muscles can actively contract, but they cannot actively relax the muscles are paired with each other, so that a muscle"s contraction causes joint motion in the other direction. But note that somatic nervous system can temporarily override autonomic control of breathing. Multinuclear one ber formed by fusion of several myoblast cells during development. Functional unit of striated muscles is 1/2 sarcomere (m line to z line) Thin laments (actin plus ca2+ regulatory proteins troponin & tropomyosin) Myosin-actin interactions: molecular (nm) motions for force generation and contraction. Muscles cross-bridge cycle: myosin in the motor protein (1) myosin head (low energy con guration) (2) myosin-binding sights myosin head (high energy con guration) (3) cross-bridge (4) power stroke (5) no atp = rigor. Ca2+ control of striated muscle contraction regulatory proteins of the thin lament. Sarcoplasmic reticulum (sr) and t-tubules in muscle contraction.

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