BIO 311 Lecture Notes - Lecture 1: Amine, Alpha And Beta Carbon, Reaction Rate

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4 types of macromolecules: nucleic acids, carbohydrates, macromolecules are often described as polymers. Polymer- a bigger molecule constructed of smaller building molecules. Stabilization of structure occurs through bonding: weaker noncovalent bonds. 20 different amino acids: construct all proteins, differences in linear sequences allows diversity, chemical characteristics allows diversity. Shape: charge, ability to hydrogen bind, chemical reactivity. Structure of amino acids: central alpha carbon. R group: hydrogen, amino group, carboxyl group. L-amino acids are the ones typically found in nature. Forms polypeptides by joining the carboxyl group of one amino acid to the amino group of another. Bacteria cell wall used the d isomer instead. Rigid and planar: allows for no rotation about the c-n bond, all atoms of the bond are on the same plane, occurs because of resonance--> electrons are redistributed. Secondary- describes spatial relationship between amino acids that are slightly farther apart: alpha helix- intrachain hydrogen bonding. Beta helix- interchain hydrogen bonding: quaternary- 2 or more interacting polypeptides.

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