BIO 122 Lecture Notes - Lecture 12: Drosophila Melanogaster, Homologous Chromosome, Mendelian Inheritance

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Chromosomes and genes are both present in pairs in diploid cells. During meiosis, chromosomes separate and alleles segregate while fertilization restores them both. Genes have a specific loci (position) along chromosomes and it is the chromosomes that undergo segregation and independent assortment homologous chromosomes during meiosis segregating the alleles at each genetic locus to different gametes. Nonhomologous chromosomes accounting for the independent assortment of the alleles for 2 or more genes located on different chromosomes. Mendel studied pea plants because a number of distinct varieties are avialable, while. Morgan studied fruit flies (drosophila melanogaster) because they produce hundreds of offspring and they only have 4 pairs of easily-distinguishable chromosomes. Wild type is a phenotype for a character (such as red eye color in flies) commonly observed in natural populations. Mutant phenotypes are traits alternative to wild type such as white eye color in flies due to changes in the wild type allele.

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