BIO 303 Lecture Notes - Lecture 27: Riboswitch, Aptamer, Antitermination

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10 May 2019
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Bind with small ligands; cause conformational change and induce second rna domain. Allows transcription of rna to proceed or not. Expression platform: capable of forming terminator structure. Tightly controlled to express required levels of gene products. Prokaryotic gene regulation occurs primarily at transcription initiation. Eukaryotic gene regulation occurs at different levels. Eukaryotes have a wide range of mechanisms for altering gene expression. Gene expression in eukaryotes occurs at different levels, including: Features of eukaryotic cells that assist in various types of gene regulation: Eukaryotic cells contain greater amounts of dna. Most genes of mrnas must be spliced, capped, and polyadenylated prior to transport from nucleus. Genetic information is carried on many chromosomes and is enclosed in a double membrane nucleus. After transcription, rnas are transported into cytoplasm for translation. Eukaryotic cells have a wide variety of half-lives. Two structural features of eukaryotes distinguish them from prokaryotes. Eukaryotic genes are situated on chromosomes that occupy a distinct location.