NS 1150 Lecture Notes - Lecture 18: Laboratory Rat, Leptin Receptor, Adipocyte

• School: Cornell University
• Department: Nutritional Science
• Course: NS 1150
• Professor: David Levitsky

Document Summary

Changed the way we thought about eating behavior today. But waited and watched animals, after some time, intake goes back to normal. Animal gains weight again and goes back to normal. Areas in the hypothalamus seem to be determining amount of body fat being regulated. There has to be some kind of lipostatin in the brain. Diets do not work! because lipostatin will keep you there. Said there was no feeding center in the brain. Said it was regulation of body weight (fat) Eating behavior is driven by physiological mechanisms involved in the regulation of body weight. Pharmaceutical companies love it- physiological and chemical- so they can sell you chemicals that they claim will change your system. Adipose cells must have a way of communicating how big they are to the brain. Two strains of obese mice were deficient in leptin. Leptin receptors found in hypothalamic structures defect in leptin receptor found in zucker rat.