GEN-3000 Lecture Notes - Lecture 13: Alu Element, Reverse Transcriptase, Selfish Dna
Document Summary
Transposable elements - repetitive and possibly mobile dnas. If they jump around and insert themselves in the middle of a gene, your gene will no longer work. Defensive mechanisms so they don"t jump too much. Transposition has the following features: staggered breaks are made in dna, te is joined to the ssdna ends of target, dna is replicated at gaps to repair (creating flanking direct repeats) They can cut themselves out and insert somewhere. Ds = smaller elements. can only move if ac element is nearby. They are smaller because they have a deletion within the element so it prevents transposase from being made. This is what she was monitoring: when did this ds element jump back out. When it jumps back out, functionality of the big c allele is restored. Late transposition small purple dot, it jumped and was later in the development of the kernel.
