ANSC 340 Lecture Notes - Lecture 20: Follicular Fluid, Follicular Phase, Prostaglandin F2Alpha
Document Summary
4 major events of follicular phase (proestrus + estrus: gonadotropin release from anterior pituitary, follicular preparation for ovulation, sexual receptivity, ovulation. Hormonal sequence of events that leads to ovulation: Estrogen reaches threshold levels and causes preovulatory lh surge &&&& increase in inhibin. Follicular growth and development occurs continuously throughout entire estrous cycle. Events include: recruitment- small antral (fluid-filled) follicles grow as a group. Small amounts of estrogen: selection- several follicles die/#s decrease. Large follicles (one or more go on to ovulate) Large amounts of estrogen: atresia- degenerative process aka cell death. Follicular waves due to: lh, fsh, estrogen, inhibin. Recruitment- high fsh, low lh, low inhibin, high estrogen. Selection- low fsh, moderate lh, low-moderate inhibin (leads to lower fsh) Dominance- low fsh, high lh, high inhibin, high estrogen. Outside: increase in granulosa cell growth leads to increase in follicular fluid. High levels of estrogen has positive effect on gnrh. Gnrh leads to lh surge (necessary for ovulation)