BIOS 20187 Lecture Notes - Lecture 9: Crispr, Phenotype, Rna Interference

• School: University of Chicago
• Department: Biological Sciences
• Course: BIOS 20187
• Professor: Malamy

Document Summary

Known gene sequence gets modified to determine what that does to the phenotype, therefore explaining what the gene does. Meant to modify the phenotype of an exisiting mutation for the end purpose of understanding genetic pathways as well as the purpose of a gene in the bigger whole. F1 screen: focuses on haploid organisms, shown phenotype in f1 generation. F2 screen: non-haploid organisms= self-fertilizing organisms shows phenotypes in f2 generation. F3 screen: organisms that fertilize each other aka sexual activity; mutant parent cross, identifying phenotypes demonstrated in the f3 generation.