CAS BI 203 Lecture Notes - Lecture 23: Homeobox Protein Nanog, Embryoid Body, Leukemia Inhibitory Factor

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Continually develop new cells throughout lifespan o 2. they can develop new cells as needed o 3. they don"t develop new cells: continually develop new cells throughout life span, ex. Neuron o when brain is formed, you have extra neurons the ones with synaptic connectivity formed will stay and the ones that don"t will go through apoptosis (can"t replenish neurons = leads to parkinson"s, alzheimer"s, Self renewal = stem cell makes a copy of itself (backup) (then stem cell divides into 2: 2. Proliferation = constant growth to get as many cells as you can get: 3. Differentiation = into what you want to cell to become. Renewal of the intestinal epithelium: niche = environment in which stem cells live in, when you lose a cell, you are replacing it with a cell that was differentiated from a stem cell.

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