CAS BI 203 Lecture Notes - Lecture 25: Dephosphorylation, Cdk Inhibitor, Phosphorylation

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Phases of the cell cycle: divided into four phases: m, g1, s, and g2, m = mitosis; followed by cytokinesis. Regulation of animal cell cycles by growth factors: availability of growth factors controls the passage through the animal cell cycle at a point in late g1 called the g1 restriction point. If growth factors are not available during g1, then cell cycle stops and cells enter a stage of the cycle called g0 (cease growth and have less protein synthesis: ex. Liver cell can regenerate and grow again/heal new cells because of overdrinking or tumor if not, then you don"t need to grow so it stays in g0 phase (no growth factors) Cell cycle checkpoints (4 in all: restriction point (g1 dna damage checkpoint)= are there enough growth factors to continue the cycle, g1/s/g2 (3 checkpoints) = dna damage checkpoints (damaged on unreplicated.

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