ESPM 108B Lecture Notes - Lecture 4: Reference Genome, Mutation Rate, Squaw

• School: Berkeley
• Department: Environmental Science, Policy, And Management
• Course: ESPM 108B
• Professor: Richard Dodd

Document Summary

9/6 widely used @ several scales of analysis. Sir , repetitive dna w/ a motif up to 6 bp ( mini satellite if move) presumed to be neutral but could be intron. Advantages : hetero i homozygote @ a certain lows highly polymorphic ( 100 alleles per lows)l high mutation rate. 40-44 per generation) on a sequencer in var . nut rates loci among means that loci can be hated to address probs @ diff time. Scales - dime . repeats have highest mutation rate mutational model explicit - most commonly assumed to follow stepwise mutational motel gmm) , but nut . involving multiple r pts . is possible . (two - phased ) tpm model can be applied. Grass of homoz recorded) of particular size alleles dueto the competitive nature of pcr can lead to pref . amp . hetero . being scored as homozyg . (inflated inbreeding) Attributes of markus forcoarse . scale studies dower.