BIOL-242 Lecture Notes - Lecture 45: Pancreatic Islets, Pancreatic Juice, Pancreatic Duct
10 Jun 2020
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Chapter 23 part 7 |function anatomy - the pancreas. Mostly retroperitoneal, deep to greater curvature of stomach. Head encircled by duodenum; tail abuts spleen. Acini (clusters of secretory cells) secrete pancreatic juice. Zymogen granules of acini cells contain proenzymes. Figure 23. 26a structure of the enzyme-producing tissue of the pancreas. Figure 23. 26b structure of the enzyme-producing tissue of the pancreas. Watery alkaline solution (ph 8) neutralizes chyme. Amylase, lipases, nucleases secreted in active form but require ions or bile for optimal activity. Trypsinogen activated to trypsin by brush border enzyme enteropeptidase. Figure 23. 27 activation of pancreatic proteases in the small intestine. Mechanisms promoting secretion and release of bile and pancreatic. Juice: chyme entering duodenum causes duodenal enteroendocrine cells to release cholecystokinin (cck) and secretin, cck (red dots) and secretin (yellow dots) enter the bloodstream, cck induces secretion of enzyme-rich pancreatic juice.
