KINE 2490 Lecture 16: Lecture 16

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Anemia: a reduction in either red blood cell volume or hemoglobin concentration. Most common symptoms: fatigue, muscle weakness, light headedness, lower oxygen concentration, hb: an iron containing pigments that carries o2 to the tissue (f: 12- 16g/100ml of blood, 14-18g/100ml of blood, values below can develop sign and symptoms, complains of fatigue tiredness) Causes: (1) impaired rbc formation, (2) excessive loss of rbc, (3) dilution situation. Mediterranean anemia gene that encode hb molecule is mutated and impacts the ability to transport oxygen. Treatment: blood transfusions, overtime is can damage heart and liver. Sickle-cell anemia hereditary problem, leads to abnormal shape of the red blood cells. Begin to clump together and cause blood cloths becomes a problem in transporting o2. Pernicious anemia related to blood cells not maturing, they may become larger than normal, lack of b12 vitamin. Hemorrhagic anemia loss of rbc though bleeding. Increase in plasma volume that increased rbc and hemoglobin production.

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