KINE 2011 Lecture Notes - Lecture 5: Cell Adhesion Molecule, Extracellular Fluid, Cell Adhesion
22 Sep 2016
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Distinguish between different types of cell junctions in terms of their function. Three different types of cell adhesions: cell adhesion molecules (cams, the extracellular matrix (ecm, specialized cell junctions. Network of fibrous proteins embedded in interstitial fluid composed of complex carbs. Interstitial fluid: provides a pathway for diffusion of nutrients, water + other water soluble traffic between blood and tissue cells. 3 major types of protein fibers in the gel: collagen: forms cable-like fibers, tensile strength (1/2 of total body protein weight, elastin: rubber-like protein fiber, stretching + recoiling (ex. Lungs: fibronectin: promotes cell adhesion, holds cells in position. Also serves as biological glue for cells. Scant in epithelial tissue; abundant in connective tissue secreted by fibroblasts (makes a lot of fibers) Cells are directly linked by 3 types of specialized cell junctions (scj) Desmosomes: act like spot rivets that anchor together to adjacent but non-touching cells, most abundant in tissues that stretch.
