BIOL 4310 Lecture Notes - Lecture 16: Freerunning, Pineal Gland, Ovulation
Document Summary
Recap: different tissues have different clocks that can tick independently but the scn symchronizes the clocks. The ovarian and reproductive clocks: the insects studied they found circadian clocks in testis rather than in ovaries, in humans, most studies were done on females and ovaries. Pituitary glands released lh and fsh that bind to the ovaries. Clocks have been found in ovaries, uterus and oviduct: ovaries follicle thecal cells. They contain cycling clock genes clock cells. Rhythmic biosynthesis as an output (hormonal) like estrogens and progesterone. Rhythmic expression of star proteins (transport protein that controls the rhythmic transport of cholesterol into the cells since it"s the main molecule that is used in the formation of the hormonal output) The clock is also sensitive to lh and fsh. Hpo: similar to hpa axis where the hypothalamus pituitary ovary leads to the rhythmic release of hormones from the ovaries (estrogen and progesterone)