Log in
HomeClass Notes1,200,000CA670,000

BIOL 3070 Lecture Notes - Lecture 8: Acidosis, Bohr Effect, Alkalosis

86 views2 pages
lilacdonkey569
2 Mar 2017
School
York University
Department
Biology
Course
BIOL 3070
Professor
Dr.Paluzzi

For unlimited access to Class Notes, a Class+ subscription is required.

Document Summary

Co2 binding would lead to decrease the binding of hemoglobin to oxygen. When co2 is low, the affinity of hb binding to oxygen would increase. When co2 is high, the affinity oh hb binding to oxygen would decrease: this leads to the unloading of oxygen in places where carbon dioxide is high, loading where co2 is low. Ph: decrease the ph, would decrease the affinity of hb-o2 and leads to unloading of oxygen, increase the ph, would increase the affinity of hb-o2 and loading of oxygen. Increasing the temperature decreases the solubility of o2 in the environment and the affinity of hb-o2 would decrease: decreasing the temperature increases the solubility of o2 in the environment and the affinity of hb-o2 would increase. They can allow the limbs to be at a lower temperature than the core body where the o2 delivery would be impaired and decreased, so o2 would not be released easily due to the increase in the affinity.

Get access

Grade+
$40 USD/m
Billed monthly
Grade+
Homework Help
Study Guides
Textbook Solutions
Class Notes
Textbook Notes
Booster Class
10 Verified Answers
Class+
$30 USD/m
Billed monthly
Class+
Homework Help
Study Guides
Textbook Solutions
Class Notes
Textbook Notes
Booster Class
7 Verified Answers

Related Documents

BIOL 3070 Lecture Notes - Lecture 9: Haldane Effect, Ion Exchange, Bicarbonate
lilacdonkey569
BIOL 3070 Lecture Notes - Lecture 13: Air Sacs, Aortic Body, Intercostal Nerves
lilacdonkey569

Related Questions

Hyperventilation leads to decreased arterial PCO2.

a. What effect will this have on blood pH and why?

b. What effect will this have on the O2-Hb dissociation curve? How will this affect O2 binding to hemoglobin at the lungs and at the tissues?

c. After a person hyperventilates, would resting respiration rate be higher than, lower than, or the same as normal? Why? d. Why would hyperventilation increase the amount of time you could hold your breath?

PHYSIOLOGY

11. A subject is connected at FRC to a bag containing 2L of 8% He, 92% O2. He rebreathes from the bag until mixing is complete; at which time the fraction of He is 4.6%. What is the value of FRC?

A. 1.15L

B. 1.48L (can you please explain this answer)

C. 2.48L

D. 3.48L

E. It cannot be calculated from the information given

The minimum time it takes a normal person to go from residual volume (RV) to total lung capacity (TLC) is less than the minimum amount of time to go from TLC to RV. The most probable explanation for this effect is:

A. the chest wall tends to spring outward when the respiratory system is at RV.

B. the chest wall is less compliant at RV.

C. inspiratory muscles are stronger than expiratory muscles.

D. the lungs have less recoil at TLC.

E. the airways tend to collapse during forced expiration. (can you please explain why this is the answer)

Two gases, A and B have the same partial pressure difference across the alveolar capillary barrier. Gas A has a molecular weight of 36 and solubility of 24 while gas B has a molecular weight of 16 and solubility of 2. What is the rate of diffusion of gas A through the barrier compared to gas B?

A. 12:1

B. 8:1 (can you explain why B is the answer?)

C. 6:4

D. 4:1

E. They are the same.

If an individual with a tidal volume of 500 ml and a dead space volume of 100 ml were to exercise and double the CO2 production, with no change in respiratory rate, what tidal volume would be required to maintain their original PCO2 of 40 mm Hg?

A. 1200 ml

B. 1100 ml

C. 1000 ml

D. 900 ml (can you explain why the answer is D?)

E. 800 ml

39. What is the total amount of oxygen in the arterial blood (in ml O2 /100ml blood) of an individual who has PO2=90mm Hg, PCO2=40mm Hg, Hb=15g/100ml, hemoglobin saturation = 95%, (solubility coefficient of O2=0.003 ml O2/100 ml blood/mm Hg; at saturation Hb binds 1.34 ml O2/g)

A. (0.95 x 15) + (95 x 0.003)

B. (90 x 1.34 x 15) + (95 x 0.003)

C. ((90 - 40) x 1.34 x 0.95) + (90 x 0.003)

D. (0.95x 1.34 x 15) + (90 x 0.003) (can you explain why the answer is D?)

E. none of the above

1. Reflexes associated with Golgitendon organs prevent skeletal muscles from

a. stretching toofar

b. contracting with too muchforce

c. accumulating too much lacticacid

d. exercising toolong

2. Why do plasma glucoseconcentrations start to decline after prolonged enduranceexercise?

a. Glucagon releasedecreases.

b. Insulin releaseincreases.

c. Cortisol releasedecreases.

d. Glycogen stores aredepleted.

3. During a graded aerobic exercise,

a. SBP gradually increases while DBP remains same or slightlydecreases.

b. SBP remains same or slightly decreases while DBP graduallyincreases.

4. Factor(s) affecting blood pressure is(are)

a. HR.

b. SV.

c. Q.

d. TPR.

e. All of above.

5. Where does waterportion of sweat come from?

a. Inside of muscle cells.

b. Urine.

c. Plasma.

6. End-diastolic volume (EDV) -end-systolic volume (ESV) =

a. cardiac output(CO).

b. mean arterial pressure(MAP).

c. stroke volume(SV).

d. ejection fraction(EF).

7. The major factor affecting blood flow is

a. viscosity ofblood.

b. length of vessel.

c. radius of vessel.

d. shear stress ofvessel.

8. Accumulation of metabolicby-products in muscle (H+,CO2, heat) leads to

a. vasoconstriction.

b. vasodilation.

c. sympatheticactivation.

d. reduced muscle bloodflow.


9. During a grated exercise until the point ofventilator threshold (VT) occurring,

a. pulmonary ventilation (VE) increases proportionally to exerciseintensity increase.

b. pulmonary ventilation (VE) increases disproportionally toexercise intensity increase.

10. Immediately stopping a steady-statesubmaximal exercise, VE steeply decreases. This decrease is dueto

a. decrease in PCO2, H+, and the coretemperature (metabolic effect).

b. decrease in neural input from CNS and feedback from activemuscle.

11. During the recovery period after asteady-state submaximal exercise, VE gradually decrease because

a. decrease in PCO2, H+, and the coretemperature (metabolic effect).

b. decrease in neural input from CNS and feedback from activemuscle.

12. Valsalvamaneuver is dangerous because

a. sore abdominal muscles.

b. a drop in blood pressure if Valsalva maneuver iscontinued.

c. a dangerous rise in blood pressure immediately afterstarting Valsalva maneuver.

d. b and c are correct.

e. All of above are correct.

13. The point atwhich pulmonary ventilation (VE) increases disproportionately withoxygen consumption (VO2) during graded exercise iscalled

a. ventilatory threshold (VT).

b. lactate threshold (LT).

c. anaerobic threshold (AT).

14. Which condition duringexercise induces the right shift of hemoglobin's oxygen-binding affinity curve(Bohr effect)?

a. ADP accumulation

b. lower pH

c. mechanical compression ofmuscle capillaries

d. local hypoxia(low O2)

15. How is bloodpressure response during submaximal exercise different between armsand legs?

a. Arms have a higher.

b. Legs have a higher.

c. They are the same

d. They can't be compared

16. Which of thefollowing does not increase the heart'sstroke volume?

a. Enhanced cardiac filling and ejection

b. Neurohormonal influence

c. Training adaptations that expand blood volume

d. Training adaptations that increase resistance to bloodflow

17. Which of the following willdecrease stroke volume (SV)?

a. increased preload

b. increasedcontractility

c. increased Calcium(Ca2+) concentrations

d. increasedafterload

18. For two athletes with sameVO2max, An athlete who has _____ lactate thresholdpredicts better performance.

a. higher

b. lower

c. It doesn