Rehabilitation Sciences 3060A/B Lecture 10: Arthritis

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Ra = yes (generically sick [v. only the joint]: normal synovial fluid. Ra involves exacerbations + remissions that progressively damage joints: affects both adults + children, begins insidiously (i. e. for no apparent reason), often beginning w/ What is ra: ra = a systemic autoimmune disease". Causes chronic inflammation of ct mainly in joints. Eventually spreads to: articular cartilage, fibrous joint capsule, surrounding ligaments & tendons. A cells = ingest/remove bacteria + debris by phagocytosis. B cells = secrete hyaluronate (binding agent, giving synovial fluid: type, type its viscous quality, articular hyaline cartilage. Composed of chondrocytes (cartilage cells) & intercellular matrix (collagen, forces of weight-bearing protein polysaccharides & water: fibrous joint capsule. Nerves sensitive to rate, direction of motion, compression, tension, vibration & pain. Ligaments = hold bones together & prevent undesirable motion. Tendons = control joint motion and convey low level muscle tone for joint stability: periosteum. U. s. prevalence among adults = ~ 10.

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