Physiology 2130 Lecture Notes - Lecture 10: Intrapleural Pressure, Functional Residual Capacity, Alveolar Macrophage

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Understand anatomy and where gas exchange occurs and doesn"t occur and how structures contribute to lungs and to gas exchange specifically, what cell types do. Lymphocytes are located in the fluid that surrounds the alveoli. Immune system role: protect body from air borne issue. Physical properties of the lungs and air pressure. Attached with the ribs and the tissues play a role in expanding and collapsing the lung itself as well as the diaphragm. Diaphragm is a muscle that we control. Ribs want to expand outward because of the muscles that surround the ribs (pulls it out) Alveolar pressure: equivalent to the atmospheric pressure. If hole in intrapleural space and pressure is lost = situation where you lose positive pressure that is pushing out and lungs can collapse. What lung tissue is made of that allows it to have elastic properties. Elastin (elastic fibers): coiled protein secreted in extracellular matrix: crosslinks: collagen fiber.

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