Pathology 4200A/B Lecture Notes - Lecture 1: Oncogene, Nicotinamide Adenine Dinucleotide, Pyruvate Dehydrogenase
4 Oct 2017
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** know this diagram: enabling replicative immortality. High levels of telomerase are expressed in cancer cells. Maintains length of chromosomal ends for infinite # of cycle. Make own blood supply via vegf to steal nutrition: tumor-promoting inflammation. If inf. persists, can become cancerous: genome instability & mutation. Pet imaging with 18fluorodeoxyglucose in a lymphoma patient: nearly all solid tumours can be diagnosed w/ this method (cid:523)unless it(cid:495)s
