Pathology 2420A Lecture 12: Module 12

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Amyloid deposits are composed of straight, non-branching fibrils. aphasia - loss of language function in which either understanding or expression of speech or both are affected. Implies a cortical lesion in the dominant hemisphere. apolipoprotein e - a protein involved in lipid transport in blood and brain. The lesion must be located in visual pathways posterior to the optic chiasm. hemiplegia - paralysis of one side of the body (often due to lesions on the opposite side of the brain). Lewy body - the characteristic round, eosinophilic, intracytoplasmic inclusions of. Neurofibrillary tangles are an element in the pathogenesis of. Wernicke"s encephalopathy - a condition observed in chronic alcoholics primarily due to thiamine deficiency; it is characterized by confusion, ataxia, and extraocular palsies. Cns is wrapped in meninges and encased in the skull and vertebrae. Meninges are three membranes (from out to in) dura, arachnoid, and pia.

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