Pathology 2420A Lecture Notes - Lecture 11: Inflammatory Bowel Disease, Helicobacter Pylori, Peptic Ulcer

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The presence of diverticula is often referred to as diverticulosis. Gut is a hollow tube connecting mouth to anus which has muscular wall and mucosal lining, which varies according to function. Composed of esophagus, stomach, small bowel, large bowel. Large bowel cecum, ascending colon, transverse colon, descending colon, sigmoid colon, rectum. Muscular valves help control movement of food and bowel contents. Esophagus and stomach are separated by lower esophageal sphincter. Stomach and duodenum separated by pyloric valve. Food and bowel contents moved by coordinated contraction of muscle layer peristalsis. Digestion begins in stomach stomach lining produces acid and pepsin (breaks down protein) Most of digestion occurs in duodenum bile from liver released here (fat absorption) Large bowel absorbs most of water and electrolytes, producing formed stools. May be asymptomatic or produce: loss of appetite, nausea, vomiting if blood present, called hematemesis, diarrhea, pain, bleeding, obstruction.

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