Pathology 2420A Lecture Notes - Lecture 7: Coronary Artery Disease, Angina Pectoris, Myocardial Infarction

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Module 7 ischemic heart disease angina pectoris - refers to the chest pain felt when the myocardium (heart muscle) receives an inadequate blood supply. The pain is typically described as a "tight" or. "clenching" feeling, and it may often be felt in the left arm as well as the chest. Also see dysrhythmia - the term arrhythmia is used even for abnormal, but regular rhythms. atheromatous plaque - the characteristic lesion of atherosclerosis which consists of a. "fibrous cap" of connective tissue, and a necrotic core (the "atheroma"); also known as a. "fibrofatty plaque" or just plain "plaque". atherosclerosis - a disease of large and medium-sized arteries. A systemic disease affecting large and medium-sized arteries. Characterized by formation of atheromas (fibrofatty plaques) which narrow (stenose) the artery lumen, resulting in reduced blood flow (ischemia) and subsequent damage or necrosis to downstream organs. Begins early in life but usually remains clinically silent until it results in disease.

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