Pathology 2420A Lecture Notes - Lecture 11: Fecal Occult Blood, Abdominal Wall, Ibuprofen

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Stomach: esophagus and stomach separated by the esophageal sphincter, stomach and duodenum by the pyloric valve. Small bowel duodenum, jejunum, ileum: ileum and cecum divided by the ileocecal valce. Large bowel cecum, ascending, transverse, descending, sigmoid and rectum. Digestion: begins in stomach with acid and pepsin (breaks down protein, most digestion occurs in duodenum. Pancreatic enzymes and bile is released in duo for absorption of fat. When they reach large bowel, its liquid; therefore large bowel absorbs water and electrolytes producing stool. Signs and symptoms of disease in the gi tract. Hematemesis vomiting of blood; indicates bleed in stomach. Most common is adenocarcinomas and then it is squamous cell carcinomas. Gastroesophageal reflux may lead to intestinal metaplasia dysplasia . Incidence is highest in males older than 50 adenocarcinoma. Risk factors for squamous cell carcinoma: alcohol, tobacco, reflux doesn"t play a role. Adenocarcinoma may be diagnosed earlier because the preceding long period of reflux is associated with heartburn.

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