Microbiology and Immunology 3820A Lecture Notes - Lecture 2: Phagocyte, Mucin, Monocyte

• School: Western University
• Department: Microbiology and Immunology
• Course: Microbiology and Immunology 3820A
• Professor: Kelly Summers

Document Summary

Explain the key properties of innate immunity. How barriers prevent pathogen entry into tissues. It is constantly ready to destroy a pathogen (immediate response: effective at stopping the majority of pathogens at an early stage before symptoms arise, deficiencies in innate immunity defenses are rare. Barriers: block pathogen entry into tissues, mechanical, chemical, biologic. Innate cells: rapidly eliminate pathogens that enter tissue. Immunity is unsuccessful: certain innate cells initiate adaptive immunity to help eliminate the pathogen. Share the same innate immunity: we are born with immune defenses, always initiated when a pathogen contacts the body, no memory: same immune response to identical pathogen with each exposure (i. e non-adaptive) Barriers: modes of pathogen entry into the body, respiratory tract, gi tract, gu tract, skin. Goblet cells: dispersed in the thick epithelial cells, these cells secrete mucin, when mucin mixes with water in the tissues, it becomes mucous.