Microbiology and Immunology 3820A Lecture Notes - Lecture 4: Superoxide Dismutase, Dental Abscess, Lung Abscess

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Mutations occurred to allow us to breath poison (o2) Aero(cid:271)es do(cid:374)"t some use none at all just means they can tolerate oxygen do(cid:374)"t ha(cid:448)e kre(cid:271)s, do(cid:374)"t ha(cid:448)e etc (cid:272)a(cid:374)"t (cid:271)reak do(cid:449)(cid:374) Story about little boy who coded and died. Dentyne line inside rectum no sensory therefore wanted to do biopsy up there. Biopsy went in and so did anaerobic bacteria into tissues. Bites: produces anaerobes into wound story of punching teeth. Clinical clues to anaerobic infection: foul odor to lesion or discharge. Infection located in proximity to mucosal surfaces: bite wounds inoculate anaerobes into wound, gas in tissues or discharges fizzing wounds, mixed organisms seen on gram stain fail to grow in aerobic culture. Nothing grow on aerobic culture but a lot of stain. Aspiration pneumonia some like chemical burn in lungs, some like pneumonia but still anaerobes involved. Bronchiectasis: esacculation of terminal airways: globs of sputum 2 layers clear with foam on top.

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