Microbiology and Immunology 3820A Lecture Notes - Lecture 4: Gram Staining, Superoxide, Human Microbiota

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There"s so much drag along surfaces that if you double the size of a pipe, you can put 16x more liquid through it. Infections commonly involving anaerobes: brain abscess, deep neck space infections, dental abscess, aspiration pneumonia (mendelson"s syndrome) (aspiration = breathing foreign objects. Infection seldom involving anaerobes: meningitis, acute sinusitis and otitis, pharyngitis, bronchitis, there are a(cid:374)aero(cid:271)es i(cid:374) si(cid:374)us/(cid:271)ro(cid:374)(cid:272)hioles/uri(cid:374)ary tra(cid:272)t (cid:271)ut they do(cid:374)"t usually cause infection b/c there is good ventilation, acute cholecystitis, spontaneous peritonitis, urinary tract infections, acute osteomyelitis. *** anaerobic specimen collection: the specimen must not be contaminated with normal flora. Therapy: surgical debridement, drainage and elimination of dead space are important for most anaerobic infections. Not typically antibiotics: antibiotics are indicated in the majority of cases, whether or not surgery has been undertaken. In normal patients, anaerobes above the diaphragm are usually susceptible to penicillin. Anaerobes below the diaphragm are penicillin resistant: large gram-positive spore-forming rods.

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