Microbiology and Immunology 2500A/B Lecture Notes - Lecture 43: Schistosomiasis, Cysticercosis, Peritoneum

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Ultrasound of scrotum or breasts for adult worms. Tpe: hypereosinophilia, high filarial ab, elevated ige. Larvae migrate to lymphatics and develop into adults which block lymph vessels. Microfilariae into blood or lungs (tropical pulmonary eosinophilia) Conventional antifilarial drugs have limited effectiveness against mansonella perstans. M. perstans, onchocerca volvulus , wucheraria bancrofti and dirofilaria immitis (dog heartworm) all have bacterial endosymbiont wolbachia, related to rickettsiae. A large part of filarial pathogenicity is due to host immune response to wolbachia. Most common tapeworm in usa and latin america. The only human tapeworm without an obligatory non-human host. Taenia solium pork tapeworm cysticercosis: neuro sx intestinal infection or. Dx eggs in stool, x rays of extremities for calcified cysts, ct scan, mri. Most common cause of hemoptysis in the world. Pleuritic pain and hemoptysis but often asymptomatic. Acute cerebral infection is uncommon but may present as meningitis. Ddx: tb, but paragonimus eggs destroyed by acid fast stain examine sputum before staining if suspicious.

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