Biology 1202B Lecture 22: Cycle-11
Document Summary
Monkey"s are the first primates to be cloned. Thalassemia hereditary blood disorder (abnormal hemoglobin = Beta thalassemia is a hereditary blood disorder. Creates abnormal hemoglobin --> leads to anemia. Because of a mutation in the intron - not in the 3"/5" splice site. When g gets mutated to an a --> get the creation of a new 3" splice site: new splice site is treated differently. Cagg is a consensus sequence for 3" splice site. The blue boxed and the orange is the same. Draw the remainder left and right and has 4 exons - should be able to draw this. Splicing occurs in bold splice signal - gets spliced out. 3" the snrnps are bound to it waits for a 5" Tag is now part of the exon - it serves as a stop sequence because tag now in orf did not get spliced out.
