Biology 1002B Lecture Notes - Lecture 23: Rhodopsin, Channelrhodopsin, Phenotype
7 Apr 2016
School
Department
Course
Professor
Document Summary
Selecion theory: before we could compare nucleoide sequence to we thought all mutaion would afect itness (posiive or negaive) Molecular clock: if the neutral theory is correct then number of mutaions should occur at a relaively constant rate over ime o o. More diferences, the longer ago the species diverged. You can determine the cytochrome c diferences if you know how long ago they diverge or vice versa. Non synonymous (replacement subsituion): much lower rate o. Most likely be harmful, and therefore would die (aren"t able to measure them if they died) Cytochrome c is constrained and can"t evolve (mutaion usually kills it) Hemoglobin can be mutated a bit and will sill work. Fibrinopepides are cloing factors and don"t need a speciic structure (can handle more mutaions-> not constrained), can evolve really fast. Coningency: the idea that each step in evoluion is dependent on all the steps before it o o.
