Biology 1002B Lecture Notes - Lecture 23: Cytochrome C, Intron, Hemoglobin

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Lecture 23: the phenotype changes only if there is a change in the nucleotide. If the change is synonymous, the phenotype does not change no evolution: neutral theor(cid:455): lots of (cid:373)utatio(cid:374) e(cid:454)ist that do(cid:374)"t affe(cid:272)t the protei(cid:374) at all. Positi(cid:448)e or (cid:374)egati(cid:448)e (cid:272)ha(cid:374)ge do (cid:374)ot ha(cid:448)e a real affe(cid:272)t si(cid:374)(cid:272)e there"s (cid:374)o ad(cid:448)a(cid:374)tage: random mutations occur at a constant rate over time. If it changes a lot, it could kill the organism: hemoglobin binds with o2. The shape could change as long as the function is the same: fibrionopeptides: clotting factors. Does not matter if the structure changes as long as they still have the same function: contingency: each step in evolution is dependent on all the steps before it. Attacks bacterial cell wall to use the nutrition from bacteria: found in blood, tears, mucus, egg white, these animals are not phylogenetically the same but they have the same digestive lysozyme.

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