Biology 1002B Lecture Notes - Lecture 6: Antimicrobial Peptides, B Cell, Hematopoietic Stem Cell

25 views6 pages

silverherring176

24 Oct 2016

School

Department

Course

Professor

For unlimited access to Class Notes, a Class+ subscription is required.

Document Summary

Milkmaids were generally immune to smallpox if they previously had cowpox: similar disease- less severe. Edward jenner (1796)- decided to see if a deliberate infection with cowpox would protect humans. Inoculated an 8 year old boy with cowpox. Smallpox has now been eradicated from the human population. Technique of infecting with a similar but less severe form of pathogen: evolved to modern vaccinations. Al take advantage of the immune system. 1st line- physical barriers that prevent the entry of pathogens. 2nd line- innate immune system- inherited mechanisms that protect the body from pathogens in a non-specific way. 3rd line- adaptive immune system found only in vertebrates, which involves inherited mechanisms that lead to the synthesis of molecules such as antibodies that target pathogens in a specific way. Prevents pathogens from entering the body: physical- body surface forms a barrier of tight junctions between epithelial cells that keeps most parasites and pathogens from entering.

Related Questions

British medical doctor, Edward Jenner, is credited with inventing smallpox vaccination - the world's first immunization. On May 14th 1796, Jenner collected secretions from a cowpox sore on the hand of a milkmaid and rub them at the scratches he made on the skin of an eight-year-old boy. Then about a month later, he injected the boy with secretions from a lesion on a smallpox patient. The child did not get smallpox, he was immune. Jenner termed his technique vaccination, which comes from the Latin term for cow, vacca.

Medical doctors began vaccinating people with special two prong needles and eventually smallpox was eradicated worldwide. The last case was documented on October 26th 1977. Eradication represents one of the greatest triumphs of modern medicine, but smallpox virus itself still exists. Stocks are kept frozen in secure laboratories at the Centers for Disease Control and Prevention (CDC) in Atlanta Georgia and in the State Research Center of Virology and Biotechnology in Koltsovo, Russia.

Imagine you are assigned to be a part of a team tasked to determine what to do with the world's remaining stores of smallpox virus. Given that this is a public health problem related to the field of microbiology and infectious disease control and prevention, address the following:

Should laboratories keep them? Or should they be destroyed?

In other words should we intentionally make a species extinct forever?

What facts do you need to make an informed decision?

If the decision were to be made today, how would you vote?

Smallpox is likely the worst infectious disease of all time killing an estimated 300 million people in the 19th century alone. It is a terrifying killer, with a death rate as high as 33% and the survivors carrying lifelong scars. British medical doctor, Edward Jenner, is credited with inventing smallpox vaccination - the world's first immunization. On May 14th 1796, Jenner collected secretions from a cowpox sore on the hand of a milkmaid and rub them at the scratches he made on the skin of an eight-year-old boy. Then about a month later, he injected the boy with secretions from a lesion on a smallpox patient. The child did not get smallpox, he was immune. Jenner termed his technique vaccination, which comes from the Latin term for cow, vacca. Medical doctors began vaccinating people with special two prong needles and eventually smallpox was eradicated worldwide. The last case was documented on October 26th 1977. Eradication represents one of the greatest triumphs of modern medicine, but smallpox virus itself still exists. Stocks are kept frozen in secure laboratories at the Centers for Disease Control and Prevention (CDC) in Atlanta Georgia and in the State Research Center of Virology and Biotechnology in Koltsovo, Russia. Imagine you are assigned to be a part of a team tasked to determine what to do with the world's remaining stores of smallpox virus. Given that this is a public health problem related to the field of microbiology and infectious disease control and prevention, address the following: Should laboratories keep them? Or should they be destroyed? In other words should we intentionally make a species extinct forever? What facts do you need to make an informed decision? If the decision were to be made today, how would you vote?

Biology 1002B Lecture Notes - Lecture 6: Antimicrobial Peptides, B Cell, Hematopoietic Stem Cell

Document Summary

Get access

Related Documents

Biology 1002B Lecture 45: Biology notes term 1, Lectures 2-11 extra notes

IMM250H1 Study Guide - Midterm Guide: Romaine Lettuce, Edward Jenner, Adaptive Immune System

MICR3001 Lecture Notes - Lecture 7: Inactivated Vaccine, Edward Jenner, Adaptive Immune System

Related Questions