Biology 1001A Lecture 6: Cycle 3. Lecture 6
3 Feb 2019
School
Department
Course
Document Summary
Less expensive over the years: now around . Relative distribution of various components of genome sequence ("junk" vs essential dna) 10% essential: 2% coding, rest is pretty much just junk, transposons, dead genes, viruses, introns, pseudogenes, These are classed as structural changes and recent scienti c research suggests that up to 9. 5% of the human genome may consist of copy number variants: eg. Indel: insertion (slippage on new strand, deletion (slippage on template, repair of double-stranded breaks by non-homologous end joining. About 2500 structural variations including mobile elements, cnv, inversions etc. Bend in backbone is due to the fact that there is a wrong base in the sequence. Excision: another mechanism: cut the new strand and put in correct nucleotides. Thymine dimer: uv photos have just the right amount of energy that can be absorbed by thymine side by side, create linking thymine covalent bonds, damage! Why did we lose this: night time!
