Biology 1001A Study Guide - Midterm Guide: Epistasis, Zygosity, Aneuploidy

• School: Western University
• Department: Biology
• Course: Biology 1001A
• Professor: Tom Haffie

Document Summary

General trends in costs of dna sequencing: advances in the field of genomics over the past quarter-century have led to substantial reductions in the cost of genome sequencing. Proportion of human genome coding for protein: 2% coding for genes of which 10% are essential. Difference between dna damage and mutation: dna damage is an abnormal chemical structure in dna, while a mutation is a change in the sequence of standard base pairs. Different types of genomic variation among humans: there are (cid:1005). (cid:1006) (cid:373)illio(cid:374) (cid:448)aria(cid:374)ts i(cid:374) hu(cid:373)a(cid:374)s, (cid:1005)/(cid:1008) of the (cid:448)aria(cid:374)t (cid:271)ases are np"s (cid:449)he(cid:374) (cid:1007)/(cid:1008) are copy number variation inversion. Each person has 300 variants in insertion of retro elements: snps(single nucleotide polymorphisms) consists of insertions, deletions and substitutions, cnv (copy number variation) consist of crossing over, mutations-changes in the dna, deletions, insertions, genetic rearrangements, mobile elements. Why african populations have more unique snps than other populations (ie. asian or.