Biology 1001A Lecture Notes - Lecture 1: Dna Mismatch Repair, Transposable Element, Dna Replication
6 Mar 2017
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In proofreading, the dna polymerase reverses & removes mispaired bases on newly synthesises dna strand as a result of a replication error. The enzyme then resumes dna synthesis in the forward direction. In dna mismatch repair, enzymes recognize distorted regions caused by mispaired base pairs and remove a section of dna that includes the mispaired base from the newly synthesized nucleotide chain. 9. 4 mobile elements: both prokaryotic and eukaryotic organisms contain transposable elements (tes) dna sequences that can move from place to place in the dna. 2 kinds of transposition: copy & past; cut & paste (see figure. 9. 17): genes of the host cell dna may become incorporated into a te and maybe carried with it to a new location. The parent copy remains at the original location. Like retrotransposons, retroviruses make a dna copy of their rna genome and insert this into the host"s chromosome. Retroviruses may have evolved from retrotransposons (see figure.
