Biology 2581B Lecture Notes - Lecture 9: Genetic Drift, Allele Frequency, Mutation
27 Feb 2019
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Document Summary
Mutation rates can be subject to mutation and genetic drift. So what if there are mutations? it depends: a snp might change the bases of the codon that might then affect the amino acid, may or may not have dramatic effects on phenotype. Compensatory mutations reverse the effects of an original mutation. These suppressions (second mutations at a diff site) could be very close like in the same codon. Start out w leucine, suffer a snp, but then suffer another snp in the same codon that restores leucine, bc the code is redundant. In process of screening, they identified gene called dracula gene. Genes can be coded on either strand: genes have to be read 3" to 5" on template dna. If looking for the coding sequence of genes, have to look both at top and bottom strand. Promoters are upstream (ish) of coding regions: which strand is transcribed depends on where the promoter is.
