Biology 2382B Lecture Notes - Lecture 6: Transferrin, Atg5, Transferrin Receptor
22 Feb 2017
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Document Summary
Cells take stuff in using phagocytosis which is a macrophage that can recognize bacteria and ingest it. Another way is through pinocytosis is like sipping. small indentations in the plasma membrane that capsulate a small amount of extra cellular fluid that is internalized. What if we want to take something from the outside and bring it inside, that is done through selective internalization of receptor mediated endocytosis. Butterball that is a way of transporting lipids. Cholesterol esters are hydrophobic so they are difficult to transport, so we coat it with this lipid like structure. Phospholipid is amiphathic, inner portion is hydrophobic and the outer portions polar and hydrophilic and can transport in water. Ldl is import so we need a reserve we can use to help maintain lipids and the body. One way to transport it is to wrap around the protein using a apolipoprotein b which helps transport it to ldl receptors in plasma membranes.
