Biochemistry 2288A Lecture Notes - Amino Acid, Dehydration Reaction, Protein Purification

• School: Western University
• Department: Biochemistry
• Course: Biochemistry 2288A
• Professor: Derek Mc Lachlin

Document Summary

1-6, 11-22, 26-35: central dogma, amino acids, protein structure, protein function, enzyme catalysis, protein purification. 164-167 peptide bonds: covalent linkage between two adjacent amino acid molecules. > chain is always written with the amino or n terminus facing left and carboxyl or c terminus facing right results in a protein with structural polarity. > or "alpha amino acid" there are around 500 amino acids but only 20 alpha amino acids. > where both the carboxyl and amino groups are attached to the alpha carbon basic structure - 19 of the 20 amino acids have this structure only proline differs - has an nh2+ instead of nh3+ amino group. > because precursor is an imino acid with a c=nh group what is its significance? amino acids are chiral - stereoisomers are possible. > with the exception of glycine only the l form is incorporated into proteins.