Biochemistry 2288A Lecture Notes - Lecture 1: Garland Science, Gene Expression, Polyadenylation

• School: Western University
• Department: Biochemistry
• Course: Biochemistry 2288A
• Professor: Susan Meakin

Document Summary

Resources: glossary in textbook, learning modules on owl (not marked), garland. Science ecb resources. , biochemistry personal trainer (back of course pack?) The human genome encodes 21 000 pro encoding genes. In any cell type <10 000 are expressed. The expression of the correct genes is essential for growth & differentiation (req right genes to come on & level of expression to be correct). Diff cell types express diff genes: the genomes are the same in brain & liver but. These set of pro expressed in the brain make it a brain. Diff pro have to express diff things to make the correct tissue. By therapeutically manipulating gene expression, we have potential to prevent or reverse disease. The central dogma: dna thru the process of transcription is converted to rna which is translated to pro. Question: at how many steps can gene expression be regulated in a eukaryotic cell?a: 2b: 3-8.