Biochemistry 2280A Lecture Notes - Lecture 24: Myeloid Tissue, Apoptosis, Chemotherapy
28 Feb 2017
School
Department
Course
Professor
Document Summary
Leading cause of death in north america. Is becoming more prevalent as the population ages. Molecular basis of cancer cancer is characterized by genetic and biochemical defects. Biochem an molecular bio provide anevues for cures. Benign: encapsulated, not that big of a problem surgeon can just go an remove it. Malignant cells are more abnormal: nto contained (not encapsulated, prone to metastasis, metastasis. Malignant tumours can metastasize, that is spread from their primary site to one or more secondary sites. Diff cancers tend to spread to diff sites. Common sites of spread are to the bones, liver, and lungs. Number of cells that do this are from 1-1000 enough to cause a huge problem. Susceptibility to cancer can be inherited: retinoblastoma (cancer of the eye, xeroderma pigmentosa (cancer of the skin, some forms of breast, prostate, ovarian, and intestinal cancers. Dna damaging agents cause cancer: radiation: uv, xrays, chemical mutagens: benzene.
