Biochemistry 2280A Lecture Notes - Lecture 24: Tumor Suppressor Gene, Xeroderma Pigmentosum, Cervical Cancer

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Biochemistry and molecular biology provide avenues for cures. Adenocarcinoma malignant, can spread, not encapsulated surgery wont remove from all sites. Malignant tumors can metastasize, spread form their primary site to one or more secondary sites. Different cancers tend to spread to different sites, common sites of spread are to the bones liver and lungs. Cells grow as benign tumor in basal lamina, cells develop ability to break away from primary tumor and spread, enter blood stream and spread to different parts of the body. Some forms of breast, prostate, ovarian and intestinal cancers. What are some of the avoidable causes of cancer. Tumor promoters phorbol esters increase cell division and cause inflammation. Certain viruses hepatitis (liver cancer) hpv (cervical cancer and others) hiv (kaposi sarcoma, non- hodgki(cid:374)"s l(cid:455)(cid:373)pho(cid:373)a) Could integrate in spot in genome that leads to cancer or cell proliferation. 30% of all cancers can be attributed to smoking (90% of lung cancer)

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