Biochemistry 2280A Lecture Notes - Lecture 13: Flavin Adenine Dinucleotide, Oxidative Phosphorylation, Intermembrane Space
28 Oct 2016
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Clicker: oxygen is a good oxidizing agent (good at removing electrons) for oxidizing nadh to. Nad+, ends up as h2o (not involved in production of co2) Overview of electron transport: nadh and fadh2 from the citric acid cycle: gives up electrons to large protein complexes in the inner mitochondrial membrane, electrons travel through, eventually go to final electron acceptor: o2. Electron transport is a proton pump: creates a larger concentration of protons on the intermembrane space side: this warrants energy for later transportation/reactions. Energetics of electron transport: redox potential drops and thus energy of the molecules drops as we move through in electron flow, energetically favourable process of passing electrons along. General order of lowest to highest electron affinity: Iron sulfur centres: flavins, ubiquinone, cytochromes, copper centers. Note: the order is not absolute since the electron carriers can be affected by the environment later, also individual circumstances of carriers: flavins:
