Biochemistry 2280A Lecture Notes - Lecture 10: Aspartate Carbamoyltransferase, Competitive Inhibition, Nicotinamide Adenine Dinucleotide Phosphate
Document Summary
Topic 8: fundamental concepts in metabolism: g vs. g , spontaneous vs. non-spontaneous, and reversible vs. irreversible reactions, driving unfavourable processes forward, metabolic pathway terms, pathway regulation, allosteric regulation and covalent modification, nadh and nadph. Delta g is affected by: properties of the molecules and, reaction conditions: temperature, pressure, concentration. The opposite reaction will be occurring but most of the time the favourable reaction will be occurring. As reaction proceeds concentration of products gets higher, eventually reach equilibrium. At equilibrium: forward reaction rate equals backwards reaction rate. Le chatelier"s principle: reactions shifts to counteract changes in concentration, changing the environment will shift the reaction to counterbalance, reaction is reversible: which way it goes can vary, the applies with all sorts of conditions. Irreversible reactions: products are strongly favoured, one sided arrow from reactants to products, note: it is not impossible but highly unlikely.