Biochemistry 2280A Lecture Notes - Lecture 8: Gibbs Free Energy, Protein Kinase, Hydrolysis
20 Feb 2017
School
Department
Course
Professor
Document Summary
G change in gibbs free energy gproducts greactants. G is affected by: properties of molecules, reaction conditions (environment) Whether a chemical reaction is spontaneous or not depends on the g that takes place. G value is calculated using the g for each molecule under standard conditions. Only information about natures of molecules involved, and not the actual conditions under which the reaction occurs in a particular system. Standard conditions are not normally met in biological systems. Based on g, differentiate between spontaneous and non-spontaneous reactions; reversible and irreversible reactions. Negative g: g of the reactants is higher than g of the products, Forward reaction is energetically favourable & reverse reaction is energetically unfavourable. Net conversion of reactants to products without addition of energy until equilibrium is reached. [products] > [reactants] if all molecules begin at equal concentration. Positive g: g of the reactants is lower than g of the products.
