Anatomy and Cell Biology 4451F/G Lecture Notes - Lecture 8: Dementia, Substantia Nigra, High-Protein Diet
4 Oct 2017
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Generally 2 different types of neurotransmitter systems in. Fast excitatory neurotransmission accomplished mainly by glutamate binding. Inhibitory neurotransmission mostly by gaba and glycine and we can say these are always inhibitory because there are only inhibitory receptors for these (at least in adult animal) Important for aspects of motor control but not for the fast action of motor control. Important in memory, mood motivation, arousal, metabolic state. If these are (cid:374)ot proper (cid:449)e"re (cid:373)e(cid:374)tally disa(cid:271)led schizophrenia, autistic. We take up amino acid nts in food, glutamate is a taste enhancer. Peptides (non classic nts) often coreleased with classic neurotransmitters. Can be excitatory or inhibitory depending on what secondary messenger cascade is activated by the g protein depends on type of g protein bound to nt receptor. Muscarinic ach receptors are metabotropic (inhibitory or excitatory) Ionotropic receptor that is very atypical is the nmda receptor. Needs glutamate in order to activate, but also needs glycine as a coactivator.
