Anatomy and Cell Biology 4451F/G Lecture 16: Lecture-16-Neuroendocrine-System
12 Sep 2018
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Document Summary
Maintain homeostasis: successful compensation, homeostasis re-established, failure to compensate, pathophysiology: illness, death. One of the major task of neuroendocrine system is to compensate for these external or internal changes so that body goes back into homeostasis. If the neuroendocrine system fails to compensate for changes, we become ill or die. It works completely differently from the neuronal system and that is due to how it transmits information. Diffuse volumetric transmission is used for modulatory neurotransmitter systems, that often can release nt not into synaptic spaces, but into extracellular fluid which then diffuses to wider distances and affect different cells at the same time. Neuroendocrine transmission: transmitter (hormones, neurohormones) release into blood stream, remote targets can reach target that are in a completely different part of the body. It is transported vast distances to reach target organs: receptor expression crucial (can only exert action at target cells because only target cells have receptors) Most important structure fro neuroendocrine system is hypothalamus.
