Anatomy and Cell Biology 2221 Lecture Notes - Lecture 2: Basal-Cell Carcinoma, Squamous Cell Carcinoma, Sebaceous Gland
27 Feb 2017
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Document Summary
Cutaneous membrane (skin: consists of two major layers: Dermis (connective tissue layer lies underneath epidermis) Keratinocytes: make tough, hard proteins, first line of defense of your skin, deeper layer and as they age they move to surface. Intraepidermal: look for evaders and help clean up damaged cells. Papillary region: 20% of dermis, blood vessels plunge up so o2 can reach. Reticular region: filled with connective tissue (collagen) to provide structure and respond to pulling and stretch, damage with a cut: leaves permanent mark. Ridges: don"t change, papillary region extends very deeply, sweat pores without ridges. Stratum granulosum: more aged cells, flattened, spread out. Stratum basale: continuous cell divison (most active) dry out. Due to collagen fibres within dermal layer. Plastic surg: cut along these lines without causing to much damage to the skin. Only way to repair damage stratum basale. Burning: harvest cells and culture in lab apply in sheets. Commercial grafts for sale from baby"s circumcision.
