PSL201Y1 Lecture Notes - Lecture 15: Tight Junction, Hemorheology, Vasoconstriction

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4 Dec 2017
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Psl201 lecture 15 part b reading notes; cardiovascular physiology 5. Flow rate of a liquid (l/min) through a pipe is directly proportional to the difference between the pressures at the two ends of the pipe (pressure gradient) and inversely proportional to the resistance of the pipe. Flow = pressure gradient / resistance = p / r. The size of the pressure gradient represents the driving force that pushes the flow of liquid through a pipe with fluid moving from high to low pressure. R (resistance) is the measure of the various forces that delay the flow of liquid through a pipe. All blood vessels have a hollow interior called the lumen where blood flows, the lumen is lined by epithelium layer called endothelium. Capillaries have a layer of endothelial cells and a basement membrane; the walls of all other blood vessels have various amount of smooth muscle and connective tissue.

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