MGY377H1 Lecture Notes - Lecture 10: Adaptive Immune System, Septic Shock, Innate Immune System

• School: UTSG
• Department: Molecular Genetics and Microbiology
• Course: MGY377H1
• Professor: William Navarre

Document Summary

Theres proteins embedded in the cell envelope, generally to help transmit signsld or move molecules across the membrane. Pipoproteins tether the outer membrane to the cell wall, gigivng it something to stick ont to, the outer membrane has a very complex structure. 2 of the alcohol groups are linked by an ester bond to the lipids, the other one is linked to a phosphate and coming off of this phosphate is a group, in this case its ethanolamine. Because of their inpermiability to charged compounds, it generates an energy potential where they can the(cid:374) use this gradie(cid:374)t t ge(cid:374)erate e(cid:374)erg(cid:455). If the (cid:272)ell does(cid:374)"t ha(cid:448)e a (cid:373)ito(cid:272)ho(cid:374)dria, its atp s(cid:455)(cid:374)thase functions at the cell membrane. O(cid:374)(cid:272)e the (cid:373)ole(cid:272)ules (cid:271)e(cid:272)o(cid:373)e (cid:272)harged, the(cid:455) do(cid:374)"t get a(cid:272)ross at all. Size also (cid:373)atters, large (cid:272)o(cid:373)pou(cid:374)ds do(cid:374)"t get a(cid:272)ross either, thus protei(cid:374)s (cid:272)a(cid:374)t get i(cid:374)/out (cid:449)ithout (cid:272)ha(cid:374)(cid:374)els. The outer membrane is very complex, and its asymmetric.