IMM250H1 Lecture : Lecture note
Document Summary
Midterm two is not cumulative 40 m/c questions type 1 and type 2 questions. If long term prime b cells their activation require linked recognition and this lr ws mhc restricted. What b cells reconizes needs to be pysically associated with what t cells recognize. B cell will indirectly using hapten carrier system, will indirectly acquire. Bystander b cell response non-specific immunoglobulin response not because unspecific but do not know specificity, that s the reason. T cells will enventually interact with professional apc that has acquired dnp carrier, chops it up, expresses determinants derived from carrier in context of mhc class 2 it expresses. Resting t helper cell wil linteract with professional antigen cell e xpressing carrier peptides becomes acivates. B cells pick up dnp covanelty linked to carrier will pick up dnap because specific for dnp. And because of covalent link will pick up carrier thus must have carrier function.
