HMB302H1 Lecture 9: Lecture 9

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16 Jan 2019
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Responses to injury cellular response: degenerative, reversible cell injury. Found in chronic inflammation tb and leprosy. Injury stimulation due to persistence of the etiological agent: repair damaged tissue is repaired by regeneration or the replacement of the damaged parenchyma & stroma by fibrous tissue (e. g. scar) In this case the bacteria was able to get into more than one lobe. Acute inflammation: exudate: vasodilation allows for the exit of fluid and plasma protein the process is termed exudation and the substance that enters the tissue area is exudate. Acute inflammation summary: response of living tissue to local injury via a series of vascular changes/blood components. 5 cardinal signs (redness, heat, swelling, pain, and loss of function) 3 basic components: changes in the local vasculature, formation of fluid exudate, formation of cellular exudate. Infiltration by mononuclear cells (macrophages, lymphocytes, and plasma cells: proliferation of fibroblasts and vascular elements.

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